General
Preferred name
DECLOXIZINE
Synonyms
UCB 1402 dihydrochloride ()
Decloxizine (dihydrochloride) ()
UCB-1402 ()
NSC289116 ()
UCB 1402 (dihydrochloride) ()
Decloxizine hydrochloride ()
Decloxizine dihydrochloride ()
Decloxizina ()
NSC-289116 ()
UCB 1402 ()
P&D ID
PD101188
CAS
13073-96-6
3733-63-9
Tags
available
drug candidate
Drug Status
investigational
Max Phase
2.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Decloxizine dihydrochloride(UCB-1402; NSC289116) is a histamine 1 receptor antagonist.
PRICE 29
PRICE 31
DESCRIPTION Decloxizine(UCB-1402; NSC289116) is a histamine 1 receptor antagonist.
DESCRIPTION The hydrochloride salt form of Decloxizine, a hydroxyzine analogue, is a histamine 1 receptor antagonist and often known as an impurity of Hydroxyzine. (BOC Sciences Bioactive Compounds)
DESCRIPTION Decloxizine is a H1 receptor antagonist (TargetMol Bioactive Compound Library)
DESCRIPTION Decloxizine dihydrochloride (UCB 1402 dihydrochloride) is a histamine 1 receptor antagonist. (TargetMol Bioactive Compound Library)
Compound Sets
5
ChEMBL Drugs
Drug Repurposing Hub
MedChem Express Bioactive Compound Library
TargetMol Bioactive Compound Library
External IDs
28
Properties
(calculated by RDKit )
Molecular Weight
340.22
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
1
Rotatable Bonds
8
Ring Count
3
Aromatic Ring Count
2
cLogP
2.4
TPSA
35.94
Fraction CSP3
0.43
Chiral centers
0.0
Largest ring
6.0
QED
0.75
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Pathway
GPCR/G protein
Immunology/Inflammation
Neuroscience
Neuronal Signaling
MOA
Histamine Receptor antagonist
Target
Histamine Receptor
H1 receptor
Solubility
10 mM in DMSO
Source data