General
Preferred name
Ginsenoside Ng-R2
Synonyms
20(S)-Notoginsenoside R2 ()
Notoginsenoside R2 ()
P&D ID
PD100323
CAS
80418-25-3
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Notoginsenoside R2 is a newly isolated notoginsenoside from Panax notoginseng, showed neuroprotective effects against 6-OHDA-induced oxidative stress and apoptosis.
PRICE 122
DESCRIPTION Notoginsenoside R2 (20(S)-Notoginsenoside R2) has neuroprotection against 6-OHDA-induced neurotoxicity, is associated with Notoginsenoside R2-mediated P90RSK and Nrf2 activation through MEK1/2-ERK1/2 pathways. (TargetMol Bioactive Compound Library)
Compound Sets
3
MedChem Express Bioactive Compound Library
HY-N0909
Selleckchem Bioactive Compound Library
notoginsenoside-r2
TargetMol Bioactive Compound Library
T6S1587
External IDs
12
Properties
(calculated by RDKit )
Molecular Weight
770.48
Hydrogen Bond Acceptors
13
Hydrogen Bond Donors
9
Rotatable Bonds
9
Ring Count
6
Aromatic Ring Count
0
cLogP
1.76
TPSA
218.99
Fraction CSP3
0.95
Chiral centers
20.0
Largest ring
6.0
QED
0.12
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Nrf2
P90RSK
Apoptosis
Apoptosis, c-Src
Pathway
Immunology/Inflammation
Source data