General
Preferred name
Nicotiflorin
Synonyms
Nictoflorin ()
Kaempferol-3-O-Rutinoside ()
Nicotifloroside ()
Nicotiflorin, Nikotoflorin, Kaempferol 3-O-¦Â-rutinoside ()
P&D ID
PD100252
CAS
17650-84-9
Tags
available
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Nicotiflorin is a flavonoid glycoside extracted from a traditional Chinese medicine Carthamus tinctorius. Nicotiflorin shows potent antiglycation activity and neuroprotection effects.
PRICE
131
DESCRIPTION
1. Nicotiflorin (Kaempferol-3-O-Rutinoside) has potential therapeutic effects on cerebral ischemic illness. 2. Nicotiflorin has protective effects on reducing memory dysfunction, energy metabolism failure and oxidative stress in multi-infarct dementia model rats.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
2
Organisms
1
Compound Sets
4
Cayman Chemical Bioactives
MedChem Express Bioactive Compound Library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
28
Molecular Weight
594.16
Hydrogen Bond Acceptors
15
Hydrogen Bond Donors
9
Rotatable Bonds
6
Ring Count
5
Aromatic Ring Count
3
cLogP
-1.39
TPSA
249.2
Fraction CSP3
0.44
Chiral centers
10.0
Largest ring
6.0
QED
0.16
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Apoptosis related,Bcl-2,Caspase,JAK,STAT
Source data
