General
Preferred name
PODOCARPUSFLAVONE A
Synonyms
P&D ID
PD100249
CAS
41583-83-9
22136-74-9
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Podocarpusflavone A is a DNA topoisomerase I inhibitor. Podocarpusflavone A has moderated anti-proliferative activity and induces cell apoptosis in MCF-7. Podocarpusflavone A is developing anti-tumor agents[1].
PRICE 120
DESCRIPTION Podocarpusflavone A is a DNA topoisomerase I inhibitor with moderate anti-proliferative activity that induces cell apoptosis in MCF-7. (TargetMol Bioactive Compound Library)
Cell lines
4
Organisms
0
Compound Sets
3
Cayman Chemical Bioactives
34613
MedChem Express Bioactive Compound Library
HY-N2198
TargetMol Bioactive Compound Library
TQ0134
External IDs
17
Properties
(calculated by RDKit )
Molecular Weight
552.11
Hydrogen Bond Acceptors
10
Hydrogen Bond Donors
5
Rotatable Bonds
4
Ring Count
6
Aromatic Ring Count
6
cLogP
5.44
TPSA
170.8
Fraction CSP3
0.03
Chiral centers
0.0
Largest ring
6.0
QED
0.19
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
Topo I
STAT3
Apoptosis
Topoisomerase
Pathway
DNA Damage/DNA Repair
JAK/STAT Signaling
Stem Cells
Cell Cycle/DNA Damage
Source data