General
Preferred name
For-Nle-Leu-Phe-Nle-Tyr-Lys-OH
Synonyms
For-Nle-Leu-Phe-Nle-Tyr-Lys-OH (TFA) ()
N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys ()
N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA ()
N-formyl-Nle-Leu-Phe-Nle-Tyr-Lys (trifluoroacetate salt) ()
P&D ID
PD099856
CAS
71901-21-8
2918767-97-0
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA (For-Nle-Leu-Phe-Nle-Tyr-Lys-OH (TFA)) (For-Nle-Leu-Phe-Nle-Tyr-Lys-OH TFA) is a formyl peptide receptor (FPR) agonist and a potent chemoattractant for human neutrophils, with its radioiodinated form retaining full biological activity. (TargetMol Bioactive Compound Library)
Compound Sets
3
Cayman Chemical Bioactives
35865
MedChem Express Bioactive Compound Library
HY-P1591
TargetMol Bioactive Compound Library
TP1164
External IDs
16
Properties
(calculated by RDKit )
Molecular Weight
823.48
Hydrogen Bond Acceptors
9
Hydrogen Bond Donors
9
Rotatable Bonds
29
Ring Count
2
Aromatic Ring Count
2
cLogP
2.36
TPSA
258.15
Fraction CSP3
0.56
Chiral centers
6.0
Largest ring
6.0
QED
0.04
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Formyl peptide receptor
formyl peptide receptor (FPR)
Pathway
GPCR/G protein
Source data