General
Preferred name
ZH8651
Synonyms
2-(4-bromophenyl)ethylamine ()
4-Bromophenethylamine ()
P&D ID
PD090729
CAS
73918-56-6
Tags
available
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
ZH8651 is an agonist of TAAR1 which can activate both Gs and Gq signal pathway. ZH8651 can used in study schizophrenia[1].
DESCRIPTION
4-Bromophenethylamine has binding affinity to 5-Hydroxytryptamine 2A receptor.
(Enamine Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
3
Enamine Bioactive Compounds
Ki Database
MedChem Express Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
16
Molecular Weight
199.0
Hydrogen Bond Acceptors
1
Hydrogen Bond Donors
1
Rotatable Bonds
2
Ring Count
1
Aromatic Ring Count
1
cLogP
1.95
TPSA
26.02
Fraction CSP3
0.25
Chiral centers
0.0
Largest ring
6.0
QED
0.78
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Trace Amine-associated Receptor (TAAR)
Pathway
GPCR/G protein
Source data
