General
Preferred name
PD088081
Synonyms
5-Bromoindole ()
P&D ID
PD088081
CAS
10075-50-0
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION 5-Bromoindole is a chemical intermediate that can be used for the synthesis of GSK-3 inhibitors and anti-cancer agents[1][2].
PRICE 29
DESCRIPTION 5-Bromoindole has inhibitory activity against cytochrome P450 2A6. (Enamine Bioactive Compounds)
DESCRIPTION 5-bromoindole is a potential inhibitor of glycogen synthase kinase 3 (GSK-3)and an important pharmaceutical chemical intermediate (TargetMol Bioactive Compound Library)
Compound Sets
4
Enamine Bioactive Compounds
EBC-03120
MedChem Express Bioactive Compound Library
HY-30236
Selleckchem Bioactive Compound Library
5-bromoindole
TargetMol Bioactive Compound Library
T7473
External IDs
20
Properties
(calculated by RDKit )
Molecular Weight
194.97
Hydrogen Bond Acceptors
0
Hydrogen Bond Donors
1
Rotatable Bonds
0
Ring Count
2
Aromatic Ring Count
2
cLogP
2.93
TPSA
15.79
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.67
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
GSK-3
Drug intermediate
Pathway
PI3K/Akt/mTOR signaling
Stem Cells
Source data