General
Preferred name
SEL-201
Synonyms
SEL201-88 ()
SLV 2436 ()
SLV-2436 ()
SLV-2436, SEL201-88 ()
SEL201 ()
P&D ID
PD087790
CAS
2095704-43-9
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION SLV-2436 is a highly potent and ATP-competitive inhibitor of MNK1 and MNK2 with IC50s of 10.8 nM and 5.4 nM, respectively.
PRICE 222
DESCRIPTION SLV-2436 (SEL201-88) is a novel effective and ATP-competitive inhibitor of MNK1 and MNK2 (IC50: 10.8/5.4 nM). (TargetMol Bioactive Compound Library)
Compound Sets
3
MedChem Express Bioactive Compound Library
HY-112113
Selleckchem Bioactive Compound Library
sel201
TargetMol Bioactive Compound Library
T4424
External IDs
7
Properties
(calculated by RDKit )
Molecular Weight
350.09
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
2
Rotatable Bonds
3
Ring Count
4
Aromatic Ring Count
4
cLogP
3.68
TPSA
76.7
Fraction CSP3
0.05
Chiral centers
0.0
Largest ring
6.0
QED
0.59
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
MNK
MNK1
MNK2
Pathway
MAPK/ERK Pathway
MAPK
Source data