General
Preferred name
Isovitexin
Synonyms
Homovitexin ()
Saponaretin ()
Apigenin-6-C-Glucoside ()
saponaretin, Apigenin-6-C-glucoside ()
P&D ID
PD087770
CAS
38953-85-4
29702-25-8
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Isovitexin is a flavonoid isolated from passion flower, Cannabis and, and the palm, possesses anti-inflammatory and anti-oxidant activities; Isovitexin acts like a JNK1/2 inhibitor and inhibits the activation of NF-¦ÊB.
PRICE 107
PRICE 130
DESCRIPTION saponaretin, an active component of many traditional Chinese medicines, shows various activities, such as anti-oxidant, anti-inflammatory, anti-alzheimer disease (AD) effects and so on.
DESCRIPTION 1. Isovitexin (Apigenin-6-C-Glucoside) exhibits a potential antioxidant activity. 2. Isovitexin shows a strong antihyperglycemic action, inhibits ??-glucosidase in vivo.
DESCRIPTION 1. Isovitexin (Apigenin-6-C-Glucoside) exhibits a potential antioxidant activity. 2. Isovitexin shows a strong antihyperglycemic action, inhibits α-glucosidase in vivo. (TargetMol Bioactive Compound Library)
Cell lines
2
Organisms
0
Compound Sets
5
AdooQ Bioactive Compound Library
A12079
Cayman Chemical Bioactives
31212
MedChem Express Bioactive Compound Library
HY-N0773
Selleckchem Bioactive Compound Library
saponaretin
isovitexin
TargetMol Bioactive Compound Library
T6S1371
External IDs
26
Properties
(calculated by RDKit )
Molecular Weight
432.11
Hydrogen Bond Acceptors
10
Hydrogen Bond Donors
7
Rotatable Bonds
3
Ring Count
4
Aromatic Ring Count
3
cLogP
0.09
TPSA
181.05
Fraction CSP3
0.29
Chiral centers
5.0
Largest ring
6.0
QED
0.3
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
NF-¦ÊB
MAPK
Metabolism
MAPK/ERK Pathway
Target
JNK
NF-κB
α-glucosidase
NF-??
¦Á-glucosidase
Immunology & Inflammation related
JNK1/2, MAPK, NF-¦ÊB, Nrf2, HO-1
MOA
Glucokinase
Source data