General
Preferred name
TECTORIDIN
Synonyms
Shekanin ()
P&D ID
PD087325
CAS
611-40-5
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Tectoridin is a isoflavone isolated from Maackia amurensis. Tectoridin is a phytoestrogen and activates estrogen and thyroid hormone receptors. Tectoridin exerts the estrogenic effects via ER-dependent genomic pathway and GPR30-dependent nongenomic pathway[1][2].
PRICE 46
DESCRIPTION Tectoridin (Shekanin) possesses an estrogenic and thyroid hormone-like agent by activating estrogen and thyroid hormone receptors. Tectoridin has anti-oxidant, anti-inflammatory and hypoglycemic activities; Tectoridin and its five metabolites inhibits the activities of lens aldose reductase in rat (IC : 1.4-15.5 ??M).
DESCRIPTION Tectoridin (Shekanin) possesses an estrogenic and thyroid hormone-like agent by activating estrogen and thyroid hormone receptors. Tectoridin has anti-oxidant, anti-inflammatory and hypoglycemic activities; Tectoridin and its five metabolites inhibits the activities of lens aldose reductase in rat (IC : 1.4-15.5 μM). (TargetMol Bioactive Compound Library)
Compound Sets
5
AdooQ Bioactive Compound Library
A12129
Cayman Chemical Bioactives
33969
MedChem Express Bioactive Compound Library
HY-N0791
Selleckchem Bioactive Compound Library
tectoridin
TargetMol Bioactive Compound Library
T3665
External IDs
24
Properties
(calculated by RDKit )
Molecular Weight
462.12
Hydrogen Bond Acceptors
11
Hydrogen Bond Donors
6
Rotatable Bonds
5
Ring Count
4
Aromatic Ring Count
3
cLogP
0.06
TPSA
179.28
Fraction CSP3
0.32
Chiral centers
5.0
Largest ring
6.0
QED
0.3
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Aldose Reductase
Estrogen Receptor/ERR
Pathway
Endocrinology/Hormones
Metabolism
Vitamin D Related/Nuclear Receptor
Source data