General
Preferred name
TETRACYCLINE
Synonyms
TC ()
P&D ID
PD087099
CAS
60-54-8
Tags
natural product
drug
available
Drug indication
Bacterial infection
Drug Status
approved
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Tetracycline is a long-used oral antibacterial. It has broad spectrum activity against aerobic and anaerobic bacteria, both Gram-negative and Gram-positive. Pseudomonas aeruginosa and Proteus spp. have natural resistance to tetracyclines. Acquired resistance to tetracycline is now commonplace. (GtoPdb)
Compound Sets
5
DrugMAP
DMZA017
DrugMAP Approved Drugs
DMZA017
Guide to Pharmacology
10927
Other bioactive compounds
Selleckchem Bioactive Compound Library
tetracycline
External IDs
16
Properties
(calculated by RDKit )
Molecular Weight
444.15
Hydrogen Bond Acceptors
9
Hydrogen Bond Donors
6
Rotatable Bonds
2
Ring Count
4
Aromatic Ring Count
1
cLogP
-0.37
TPSA
181.62
Fraction CSP3
0.41
Chiral centers
5.0
Largest ring
6.0
QED
0.33
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Therapeutic Class
Antibiotics
Target
Antibiotics,Antineoplastic and Immunosuppressive Antibiotics,Bacterial
Source data