General
Preferred name
BAICALEIN TRIMETHYL ETHER
Synonyms
5,6,7-trimethoxyflavone ()
P&D ID
PD086879
CAS
973-67-1
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION 5,6,7-Trimethoxyflavone is a flavonoid compound that can be isolated from plants Callicarpa japonica. 5,6,7-Trimethoxyflavone exhibits antiviral and anti-inflammatory activities through inhibition of NF-¦ÊB/AP-1/STAT signaling pathway[1][2].
PRICE 72
DESCRIPTION 5,6,7-Trimethoxyflavone, a natural product extracted from Japanese Callicarpa, acts as a p38-?? MAPK inhibitor and exhibits anti-inflammatory properties.
DESCRIPTION 5,6,7-Trimethoxyflavone, a natural product extracted from Japanese Callicarpa, acts as a p38-α MAPK inhibitor and exhibits anti-inflammatory properties. (TargetMol Bioactive Compound Library)
Cell lines
4
Organisms
0
Compound Sets
4
Cayman Chemical Bioactives
40289
MedChem Express Bioactive Compound Library
HY-110398
Selleckchem Bioactive Compound Library
trimethoxyflavone
TargetMol Bioactive Compound Library
T7051
External IDs
23
Properties
(calculated by RDKit )
Molecular Weight
312.1
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
0
Rotatable Bonds
4
Ring Count
3
Aromatic Ring Count
3
cLogP
3.49
TPSA
57.9
Fraction CSP3
0.17
Chiral centers
0.0
Largest ring
6.0
QED
0.74
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
p38 MAPK
Antiviral,Bacterial
AP-1
CMV
Enterovirus
HSV
STAT
Pathway
Anti-infection
Immunology/Inflammation
JAK/STAT Signaling
NF-κB
Stem Cell/Wnt
MAPK
NF-¦ÊB
Source data