General
Preferred name
TC-2216
Synonyms
7-(pyridin-3-yl)-1,7-diazaspiro[4.4]nonane ()
TC-2216 trihydrochloride ()
P&D ID
PD085998
CAS
646055-67-6
1159824-71-1
Tags
available
drug candidate
Drug indication
Mood disorder
Drug Status
investigational
Max Phase
Phase 1
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
6
ChEMBL Drugs
DrugMAP
Enamine BioReference Compounds
Ki Database
LSP-MoA library (Laboratory of Systems Pharmacology)
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
15
Properties
(calculated by RDKit )
Molecular Weight
203.14
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
1
Rotatable Bonds
1
Ring Count
3
Aromatic Ring Count
1
cLogP
1.41
TPSA
28.16
Fraction CSP3
0.58
Chiral centers
1.0
Largest ring
6.0
QED
0.75
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Source data
