General
Preferred name
Taspoglutide
Synonyms
Taspoglutide (acetate) ()
P&D ID
PD085682
CAS
275371-94-3
1022150-16-8
Tags
available
drug candidate
Drug indication
Type-1 diabetes
Drug Status
investigational
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Taspoglutide is a long-acting peptidic GLP-1 receptor agonist, with alpha-aminoisobutyric acid substitutions replacing the Ala8 and Gly35 residues of the endogenous hGLP-1(7-36)NH2 peptide . It is resistant to protelytic cleavage by dipeptidyl peptidase-4.
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
5
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
15
Molecular Weight
3337.71
Hydrogen Bond Acceptors
46
Hydrogen Bond Donors
49
Rotatable Bonds
108
Ring Count
6
Aromatic Ring Count
6
cLogP
-12.83
TPSA
1385.09
Fraction CSP3
0.57
Chiral centers
29.0
Largest ring
6.0
QED
0.01
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Source data
