General
Preferred name
PYRIDABEN
Synonyms
Pyridaben-d13 ()
P&D ID
PD085446
CAS
96489-71-3
2468638-05-1
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE 29
DESCRIPTION Pyridaben is a mitochondrial electron transport inhibitor (METI) acaricide that promotes the formation of damaging oxygen and nitrogen radicals. Pyridaben selectively inhibits complex I (NADH dehydrogenase) with an IC50 value of 2.4 nM (assay sites: rat liver and bovine heart mitochondria). Pyridaben also significantly inhibits rat mitochondrial mtNOS function[1][2].
DESCRIPTION Pyridaben is a METI acaricide that inhibits mitochondrial electron transport at complex I (METI; Ki = 0.36 nmol/mg protein in rat brain mitochondria). (TargetMol Bioactive Compound Library)
Cell lines
0
Organisms
1
Compound Sets
6
Cayman Chemical Bioactives
25821
39259
CZ-OPENSCREEN Bioactive Library
EU-OPENSCREEN Bioactive Compound Library
EOS102302
MedChem Express Bioactive Compound Library
HY-B0817
ReFrame library
TargetMol Bioactive Compound Library
T5114
External IDs
29
Properties
(calculated by RDKit )
Molecular Weight
364.14
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
0
Rotatable Bonds
3
Ring Count
2
Aromatic Ring Count
2
cLogP
5.24
TPSA
34.89
Fraction CSP3
0.47
Chiral centers
0.0
Largest ring
6.0
QED
0.7
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
NADH dehydrogenase(NADH:ubiquinone oxidoreductase
Electron transport complex I)
Parasite
MOA
Electron transport inhibitor
Pathway
Membrane Transporter/Ion Channel
Metabolism
Microbiology/virology
Anti-infection
Source data