General
Preferred name
GANODERIC ACID C2
Synonyms
P&D ID
PD082644
CAS
103773-62-2
Tags
available
probe
Probe info
Probe type
calculated probe
Probe selectivity
protein-selective
Probe sources
Probe Miner (suitable probes)
Probe targets
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Ganoderic acid C2 is a bioactive triterpenoid in Ganoderma lucidum. Ganoderic acid C2 possesses the potential anti-tumor bioactivity, antihistamine, anti-aging and cytotoxic effects. Ganoderic acid C2 is the inhibitor for aldose reductase with an IC50 of 43.8 ¦ÌM[1][2].
PRICE 232
DESCRIPTION Ganoderic acid C2 has anti-inflammatory,and anti-tumor-promoting activities. Ganoderic acid C2 can inhibit histamine release, it also has inhibitory effects on the induction of Epstein-Barr Virus early antigen. Ganoderic acid C2 exhibits high inhibitory activity against the rat lens aldose reductase (IC50 = 3.8 ??M).
DESCRIPTION Ganoderic acid C2 has anti-inflammatory,and anti-tumor-promoting activities. Ganoderic acid C2 can inhibit histamine release, it also has inhibitory effects on the induction of Epstein-Barr Virus early antigen. Ganoderic acid C2 exhibits high inhibitory activity against the rat lens aldose reductase (IC50 = 3.8 µM). (TargetMol Bioactive Compound Library)
Cell lines
3
Organisms
0
Compound Sets
3
MedChem Express Bioactive Compound Library
HY-N1517
Probe Miner (suitable probes)
P01375/732667
TargetMol Bioactive Compound Library
TN1661
External IDs
13
Properties
(calculated by RDKit )
Molecular Weight
518.32
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
4
Rotatable Bonds
6
Ring Count
4
Aromatic Ring Count
0
cLogP
3.92
TPSA
132.13
Fraction CSP3
0.83
Chiral centers
10.0
Largest ring
6.0
QED
0.42
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Endocrinology/Hormones
GPCR/G protein
Immunology/Inflammation
Metabolism
Neuroscience
Metabolic Enzyme/Protease
Target
Aldose Reductase
Histamine Receptor
Immunology/Inflammation related
Source data