General
Preferred name
TILIROSIDE
Synonyms
Tribuloside ()
P&D ID
PD082091
CAS
20316-62-5
22153-44-2
Tags
available
probe
drug candidate
Drug indication
Discovery agent
Probe info
Probe type
calculated probe
Probe selectivity
protein-selective
Probe sources
Probe targets
[[ compound.targets[t].gene_name ]]
Probe control
Probe control not defined
Orthogonal probes
2
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Tribuloside is a flavonoid that can be isolated from Tribulus terrestris L[1]. Tribuloside exhibits anti-mycobacterial activity against the non-pathogenic Mycobacterium species with a minimum inhibitory concentration (MIC) of 5.0 mg/mL. Tribuloside has 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity[2].
PRICE
216
DESCRIPTION
Tiliroside, a glycosidic flavonoid, possesses anti-diabetic activities. Tiliroside is a noncompetitive inhibitor of ¦Á-amylase with a Ki value of 84.2 ¦ÌM. Tiliroside inhibits carbohydrate digestion and glucose absorption in the gastrointestinal tract[1].
DESCRIPTION
A new cinnamolyglycoflavonoid 3-cinnamoyltribuloside (1), its precursor Tribuloside (Tiliroside) A and two known flavonoid glycosides afzelin and astilbin were isolated from Heritiera littoralis Dryand (Sterculiaceae) ethanolic leaf extract.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
3
Organisms
0
Compound Sets
7
AdooQ Bioactive Compound Library
Cayman Chemical Bioactives
DrugMAP
Probe Miner (suitable probes)
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
35
Molecular Weight
594.14
Hydrogen Bond Acceptors
13
Hydrogen Bond Donors
7
Rotatable Bonds
7
Ring Count
5
Aromatic Ring Count
4
cLogP
1.73
TPSA
216.58
Fraction CSP3
0.2
Chiral centers
5.0
Largest ring
6.0
QED
0.12
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Bacterial
Interleukin Related
Microphthalmia Associated Transcription Factor (MITF)
Phosphodiesterase (PDE)
PKA
TRP Channel
Tyrosinase
Interleukins, Antioxidant, TNF-alpha, p38 MAPK, STAT, Bcl-2, PDE
MOA
Antioxidant
Pathway
Microbiology/virology
Anti-infection
Cell Cycle/DNA Damage
Immunology/Inflammation
Membrane Transporter/Ion Channel
Metabolic Enzyme/Protease
Neuronal Signaling
Stem Cell/Wnt
TGF-beta/Smad
Source data
