General
Preferred name
OUL35
Synonyms
NSC39047 ()
OUL 35 ()
P&D ID
PD080370
CAS
6336-34-1
71767-67-4
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION OUL35 (NSC39047) is a potent and selective inhibitor of ARTD10 (PARP-10), with an IC50 of 329 nM[1].
PRICE 31
DESCRIPTION OUL35 is reported as a PARP10 inhibitor . (GtoPdb)
DESCRIPTION OUL 35 is a PARP-10 inhibitor with IC50 value of 0.329 μM. It can rescue HeLa cells from ARTD10 induced apoptotic cell death. (BOC Sciences Bioactive Compounds)
DESCRIPTION OUL35 (NSC-39047) is a selective PARP-10 inhibitor, and small-molecule ARTD10 inhibitor. OUL35 has been shown to rescue cells from ARTD10-induced cell death. (TargetMol Bioactive Compound Library)
DESCRIPTION Potent hepatoselective glucokinase activator (Tocris Bioactive Compound Library)
Cell lines
1
Organisms
0
Compound Sets
8
BOC Sciences Bioactive Compounds
oul-35-cas-6336-34-1-item-169496
Cayman Chemical Bioactives
28845
Guide to Pharmacology
13119
Mcule NIBR MoA Box Subset
MCULE-8450176580
MedChem Express Bioactive Compound Library
HY-123512
Novartis Chemogenetic Library (NIBR MoA Box)
TargetMol Bioactive Compound Library
T9024
Tocris Bioactive Compound Library
6344
External IDs
16
Properties
(calculated by RDKit )
Molecular Weight
256.08
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
2
Rotatable Bonds
4
Ring Count
2
Aromatic Ring Count
2
cLogP
1.68
TPSA
95.41
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.87
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
ARTD10
PARP
PARP10
Primary Target
Poly(ADP-ribose) Polymerase
MOA
Inhibitor
PARP10 inhibitor
Member status
member
Pathway
Cell Cycle/DNA Damage
Epigenetics
Chromatin/Epigenetic
DNA Damage/DNA Repair
Source data