General
Preferred name
TAPI-1
Synonyms
(2R)-TAPI-1 ()
P&D ID
PD080151
CAS
163847-77-6
Tags
available
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
TAPI-1 is a potent inhibitor of matrix metalloproteinases and TACE (TNF-α convertase/ADAM17/α-secretase).
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
2
BOC Sciences Bioactive Compounds
MedChem Express Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
10
Molecular Weight
499.28
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
6
Rotatable Bonds
13
Ring Count
2
Aromatic Ring Count
2
cLogP
1.0
TPSA
162.65
Fraction CSP3
0.46
Chiral centers
3.0
Largest ring
6.0
QED
0.18
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Metabolic Enzyme/Protease
Target
MMP
Source data
