General
Preferred name
MIF
Synonyms
7-Methoxyisoflavone ()
P&D ID
PD078612
CAS
1621-56-3
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION 7-Methoxyisoflavone is an isoflavone derivative and also an activator of adenosine monophosphate-activated protein kinase (AMPK).
PRICE 29
DESCRIPTION 7-Methoxyisoflavone is a synthetic isoflavone and an isomer of 7-methoxyflavone. It inhibits ALDH-2 (aldehyde dehydrogenase 2) and MAO with IC50 values of 1.2 and 8 µM, respectively. (Enamine Bioactive Compounds)
DESCRIPTION 7-Methoxyisoflavone is an activator of adenosine monophosphate-activated protein kinase (AMPK). (TargetMol Bioactive Compound Library)
Compound Sets
5
Cayman Chemical Bioactives
33419
Enamine Bioactive Compounds
EBC-157155
MedChem Express Bioactive Compound Library
HY-N6631
Selleckchem Bioactive Compound Library
7-methoxyisoflavone
TargetMol Bioactive Compound Library
T7327
External IDs
18
Properties
(calculated by RDKit )
Molecular Weight
252.08
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
0
Rotatable Bonds
2
Ring Count
3
Aromatic Ring Count
3
cLogP
3.47
TPSA
39.44
Fraction CSP3
0.06
Chiral centers
0.0
Largest ring
6.0
QED
0.7
Structural alerts
2
aggregator (Aggregator Advisor)
Aggregators
aggregator (ZINC)
Aggregators
Custom attributes
(extracted from source data)
Target
AMPK
Pathway
Chromatin/Epigenetic
PI3K/Akt/mTOR signaling
Epigenetics
PI3K/Akt/mTOR
Source data