General
Preferred name
BQR695
Synonyms
NVP-BQR695 ()
BQR-695 ()
P&D ID
PD078509
CAS
1513879-21-4
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION BQR-695 is a PI4KIII¦Â inhibitor with IC50s of 80 and 3.5 nM for human PI4KIII¦Â and Plasmodium variant of PI4KIII¦Â, respectively.
PRICE 74
DESCRIPTION BQR-695 (NVP-BQR695) is a phosphatidylinositol 4-kinase (PI4K) inhibitor with IC50s of 80 and 3.5 nM for human PI4KIII?? and Plasmodium variant of PI4KIII??, respectively.
DESCRIPTION BQR695 is a potent and selective PI4K inhibitor exhibiting potency against both human PI4KIIIβ and Plasmodium falciparum asexual blood stages (IC50 values of 90 nM and 71 nM, respectively). (BOC Sciences Bioactive Compounds)
DESCRIPTION BQR-695 (NVP-BQR695) is a phosphatidylinositol 4-kinase (PI4K) inhibitor with IC50s of 80 and 3.5 nM for human PI4KIIIβ and Plasmodium variant of PI4KIIIβ, respectively. (TargetMol Bioactive Compound Library)
Compound Sets
6
Axon Medchem Screening Library
2801
BOC Sciences Bioactive Compounds
bqr695-cas-1513879-21-4-item-55240
Cayman Chemical Bioactives
27482
MedChem Express Bioactive Compound Library
HY-18748
Selleckchem Bioactive Compound Library
bqr695
TargetMol Bioactive Compound Library
T4220
External IDs
10
Properties
(calculated by RDKit )
Molecular Weight
352.15
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
2
Rotatable Bonds
6
Ring Count
3
Aromatic Ring Count
3
cLogP
2.47
TPSA
85.37
Fraction CSP3
0.21
Chiral centers
0.0
Largest ring
6.0
QED
0.71
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
Parasite
PI3KIIIβ
PI4K
PI4K inhibitor
Pathway
Microbiology/virology
PI3K/Akt/mTOR signaling
Anti-infection
PI3K/Akt/mTOR
Source data