General
Preferred name
Pocapavir
Synonyms
SCH-48973 ()
V-073 ()
P&D ID
PD078468
CAS
146949-21-5
Tags
available
drug candidate
Drug Status
investigational
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Pocapavir (SCH-48973) is an orally active capsid inhibitor. Pocapavir prevents virion uncoating upon entry into the cell. Pocapavir has antiviral activity against polioviruses. Pocapavir also inhibits enterovirus infections[1].
PRICE 60
DESCRIPTION Pocapavir has been found to be an antienterovirus agent that could probably be effctive against enterovirus infections. The Phase-II trial for Poliomyelitis has not been reported yet since 2012. (BOC Sciences Bioactive Compounds)
DESCRIPTION Pocapavir (SCH-48973) is an investigational enterovirus (EV) capsid inhibitor. (TargetMol Bioactive Compound Library)
Cell lines
0
Organisms
18
Compound Sets
8
BOC Sciences Bioactive Compounds
pocapavir-cas-146949-21-5-item-475808
Cayman Chemical Bioactives
37349
Drug Repurposing Hub
DrugBank
DB17736
MedChem Express Bioactive Compound Library
HY-104074
Pandemic Response Box
ReFrame library
TargetMol Bioactive Compound Library
T4492
External IDs
17
Properties
(calculated by RDKit )
Molecular Weight
422.02
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
0
Rotatable Bonds
7
Ring Count
3
Aromatic Ring Count
3
cLogP
6.81
TPSA
27.69
Fraction CSP3
0.14
Chiral centers
0.0
Largest ring
6.0
QED
0.42
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
Antiviral
Enterovirus
MOA
Antiviral inhibitor
Enterovirus capsid inhibitor
Pathway
Anti-infection
Immunology/Inflammation
Microbiology/virology
Solubility
In vitro:<br/>10 mM in DMSO
Source data