General
Preferred name
LARAZOTIDE
Synonyms
LARAZOTIDE ACETATE ()
AT-1001 ()
AT1001 ()
Larazotide (acetate) ()
AT-2347 ()
AT-1001 (LARAZOTIDE ACETATE) ()
P&D ID
PD077564
CAS
881851-50-9
745055-08-7
258818-34-7
Tags
available
drug candidate
Drug indication
Autoimmune diabetes
Drug Status
investigational
Max Phase
Phase 3
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
10
AdooQ Bioactive Compound Library
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugMAP
MedChem Express Bioactive Compound Library
Novartis Chemogenetic Library (NIBR MoA Box)
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
24
Properties
(calculated by RDKit )
Molecular Weight
725.41
Hydrogen Bond Acceptors
10
Hydrogen Bond Donors
9
Rotatable Bonds
21
Ring Count
1
Aromatic Ring Count
0
cLogP
-3.18
TPSA
301.32
Fraction CSP3
0.72
Chiral centers
5.0
Largest ring
5.0
QED
0.06
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Cytoskeletal Signaling
cytoskeleton
Target
Gap Junction Protein
Member status
member
MOA
Zonulin Receptor Antagonists
tight junction regulator
Source data
