General
Preferred name
TEBUCONAZOLE
Synonyms
Tebuconazole-d9 ()
P&D ID
PD077301
CAS
80443-41-0
107534-96-3
1246818-83-6
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Tebuconazole is an orally active agricultural azole fungicide which can also inhibit CYP51 with IC50s of 0.9 and 1.3 ¦ÌM for Candida albicans CYP51 (CaCYP51) and truncated Homo sapiens CYP51 (¦¤60HsCYP51), respectively. Tebuconazole induces lipid accumulation and oxidative stress in HepG2 Cells. Tebuconazole decreases MAC-T cells viability and proliferation, induces ER-stress-mediated apoptosis and increases oxidative stress levels in MAC-T cells[1][2][3][4][5][6].
PRICE 29
DESCRIPTION Tebuconazole is an agricultural azole fungicide. It can also inhibit CYP51 (IC50s: 0.9 and 1.3 ??M for Candida albicans CYP51 and truncated Homo sapiens CYP51, respectively).
DESCRIPTION Tebuconazole is a triazole fungicide that is active against both seed and foliar fungi. (Enamine Bioactive Compounds)
DESCRIPTION Tebuconazole is an agricultural azole fungicide. It can also inhibit CYP51 (IC50s: 0.9 and 1.3 μM for Candida albicans CYP51 and truncated Homo sapiens CYP51, respectively). (TargetMol Bioactive Compound Library)
Cell lines
0
Organisms
2
Compound Sets
6
Cayman Chemical Bioactives
24052
33287
Enamine Bioactive Compounds
EBC-12990
EU-OPENSCREEN Bioactive Compound Library
EOS100298
MedChem Express Bioactive Compound Library
HY-B0852
TargetMol Bioactive Compound Library
T17022
The Spectrum Collection
External IDs
27
Properties
(calculated by RDKit )
Molecular Weight
307.15
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
1
Rotatable Bonds
5
Ring Count
2
Aromatic Ring Count
2
cLogP
3.34
TPSA
50.94
Fraction CSP3
0.5
Chiral centers
1.0
Largest ring
6.0
QED
0.92
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Metabolism
Microbiology/virology
Anti-infection
Metabolic Enzyme/Protease
Target
Apoptosis
Cytochrome P450
Fungal
CYP51
Source data