General
Preferred name
ARGIPRESTOCIN
Synonyms
Arginine vasotocin trifluoroacetate salt ()
Arginine Vasotocin (trifluoroacetate salt) ()
Argiprestocine ()
8-arginineoxytocin ()
Arginine Vasotocin ()
Argiprestocina ()
P&D ID
PD077112
CAS
113-80-4
Tags
drug candidate
available
Drug Status
investigational
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Arginine vasotocin (AVT) is the non-mammalian homolog of arginine vasopressin (AVP) and serves as an important modulator of social behavior in addition to its peripheral functions related to osmoregulation, reproductive physiology, and stress hormone release. AVT is aslo homologous to arginine vasopressin in mammals and is endogenously released from the neurohypophysis primarily in response to hyperosmotic stimuli and associated cellular dehydration. Arginine vasotocin is a nonapeptide hormone agonist of the AVT receptor with EC50 of 13 nM for eliciting membrane.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
3
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
ChEMBL Drugs
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
25
Molecular Weight
1049.45
Hydrogen Bond Acceptors
16
Hydrogen Bond Donors
15
Rotatable Bonds
19
Ring Count
3
Aromatic Ring Count
1
cLogP
-5.39
TPSA
461.43
Fraction CSP3
0.58
Chiral centers
9.0
Largest ring
20.0
QED
0.03
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Solubility
Soluble in DMSO.
Source data
