General
Preferred name
GSK-3β inhibitor 2
Synonyms
GSK-3β inhibitor 3 [PMID: 25845281] ()
P&D ID
PD076517
CAS
1702428-31-6
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION This compound is a selective GSK-3β inhibitor that was initially discovered in and subsequently included as one of the active moeities in the novel dual GSK-3β/acetylcholinesterase inhibitor . (GtoPdb)
Compound Sets
2
Guide to Pharmacology
9811
MedChem Express Bioactive Compound Library
HY-130795
External IDs
10
Properties
(calculated by RDKit )
Molecular Weight
318.08
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
2
Rotatable Bonds
5
Ring Count
3
Aromatic Ring Count
2
cLogP
1.66
TPSA
107.2
Fraction CSP3
0.29
Chiral centers
0.0
Largest ring
6.0
QED
0.87
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Pathway
PI3K/Akt/mTOR
Stem Cell/Wnt
Target
GSK-3
Source data