General
Preferred name
Tofogliflozin (hydrate)
Synonyms
CSG-452 hydrate ()
TOFOGLIFLOZIN HYDRATE ()
Tofogliflozin(CSG 452) ()
Tofogliflozin monohydrate ()
Tofogliflozin hydrate ()
Tofogliflozina ()
Tofogliflozine ()
CSG452 ()
Tofogliflozin ()
TOFOGLIFLOZIN ()
P&D ID
PD076456
CAS
1201913-82-7
Tags
available
drug
Drug Status
approved
Max Phase
4.0
First approval
2014
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
7
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
EU-OPENSCREEN Bioactive Compound Library
MedChem Express Bioactive Compound Library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
10
Properties
(calculated by RDKit )
Molecular Weight
404.18
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
4
Rotatable Bonds
4
Ring Count
4
Aromatic Ring Count
2
cLogP
0.17
TPSA
130.88
Fraction CSP3
0.45
Chiral centers
5.0
Largest ring
6.0
QED
0.57
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
GPCR/G protein
Immunology/Inflammation
NF-¦ÊB
Membrane Transporter/Ion Channel
Metabolic Enzyme/Protease
NF-κB
Target
SGLT2
ROS
Reactive Oxygen Species
SGLT
Source data
