General
Preferred name
Imidazoleacetic acid
Synonyms
IMIDAZOL-4-YLACETIC ACID SODIUM SALT ()
Imidazole-4-acetic acid hydrochloride ()
2-(1H-Imidazol-5-yl)acetic acid hydrochloride ()
Imidazole-4-acetic acid ()
I4AA ()
(4-Imidazolyl)acetic acid hydrochloride ()
4-Imidazoleacetic acid hydrochloride ()
Imidazoleacetic acid (hydrochloride) ()
Imidazolyl-4-acetic acid ()
Imidazolyl-4-acetic acid (hydrochloride) ()
Imidazole-4(5)-acetic Acid Hydrochloride ()
Imidazoleacetic acid hydrochloride ()
IMIDAZOLE ACETIC ACID ()
P&D ID
PD075339
CAS
56368-58-2
3251-69-2
645-65-8
66298-09-7
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Imidazoleacetic acid hydrochloride is a ¦Ã-aminobutyric acid receptor agonist. Imidazoleacetic acid hydrochloride inhibits GABA-T in a non-competitive manner, with a Ki value of 0.34 mM. Imidazoleacetic acid hydrochloride increases total free GABA in brain[1][2][3].
PRICE 29
DESCRIPTION Imidazoleacetic acid hydrochloride (I4AA) is an imidazole derivative with potential antituberculosis properties. It also used in the preparation of acyl guanidine inhibitors of ??-secretase.
DESCRIPTION Imidazoleacetic acid is an endogenous ligand that stimulates imidazole receptors.
DESCRIPTION Competitive antagonist at GABA-C receptors (LOPAC library)
DESCRIPTION 4-Imidazoleacetic acid hydrochloride is a competitive antagonist of GABAC receptors. (BOC Sciences Bioactive Compounds)
DESCRIPTION Imidazoleacetic acid hydrochloride (I4AA) is an imidazole derivative with potential antituberculosis properties. It also used in the preparation of acyl guanidine inhibitors of β-secretase. (TargetMol Bioactive Compound Library)
Compound Sets
8
BOC Sciences Bioactive Compounds
4-imidazoleacetic-acid-hydrochloride-cas-3251-69-2-291199
DrugMatrix
Ki Database
Imidazole-4-acetic acid
LOPAC library
MedChem Express Bioactive Compound Library
HY-W007686
HY-113413
Selleckchem Bioactive Compound Library
imidazole-4-5-acetic-acid-hydrochloride
TargetMol Bioactive Compound Library
T4753
The Spectrum Collection
External IDs
73
Properties
(calculated by RDKit )
Molecular Weight
126.04
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
2
Ring Count
1
Aromatic Ring Count
1
cLogP
0.04
TPSA
65.98
Fraction CSP3
0.2
Chiral centers
0.0
Largest ring
5.0
QED
0.59
QED
0.59
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
GABA-C
Target
Endogenous Metabolite
tuberculosis
GABA Receptor
MOA
Antibiotic
Pathway
Metabolism
Microbiology/virology
Metabolic Enzyme/Protease
Membrane Transporter/Ion Channel
Neuronal Signaling
Source data