General
Preferred name
titanium dioxide
Synonyms
P&D ID
PD073666
CAS
13463-67-7
12036-20-3
1317-80-2
100292-32-8
1317-70-0
Tags
available
contains metal
inorganic
drug
Approved by
FDA
First approval
2006
Drug Status
approved
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PHARMACODYNAMICS As Sunscreen agent : protect the skin from sunburn and erythema by absorbing or blocking ultraviolet radiation.; Biocompatible Materials : Synthetic or natural materials, other than drugs, that are used to replace or repair any body tissues or bodily function.
TOXICITY Rat - LD50 Intratracheal (>100ug/kg ) Effects: Structural or functional changes in bronchi and trachea.; There is inadequate evidence in humans for the carcinogenicity of titanium dioxide. Cancer in experimental animals: There is sufficient evidence in experimental animals for the carcinogenicity of titanium dioxide. Overall evaluation: Titanium dioxide is possibly carcinogenic to humans (Group 2B).
Compound Sets
4
DrugBank
DB09536
DrugBank Approved Drugs
DB09536
DrugCentral
4237
DrugCentral Approved Drugs
4237
External IDs
20
Properties
(calculated by RDKit )
Molecular Weight
79.94
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
0
Rotatable Bonds
0
Ring Count
0
Aromatic Ring Count
0
cLogP
-0.24
TPSA
34.14
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
0.0
QED
0.38
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Source data