General
Preferred name
DACISTEINE
Synonyms
N,S-Diacetyl-L-cysteine ()
Mucothiol ()
Dacisteina ()
P&D ID
PD073603
CAS
18725-37-6
Tags
drug
available
Drug Status
approved
investigational
Max Phase
2.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Dacisteine (N,S-Diacetyl-L-cysteine) is a cysteine derivative and displays a less New Delhi metallo-beta-lactamase-1 (NDM-1) inhibitor with an IC50 value of 1000 ¦ÌM[1]. Dacisteine can be used for the treatment of cardiovascular and cerebrovascular diseases caused by platelet aggregation[2].
PRICE 29
DESCRIPTION Dacisteine (N,S-Diacetyl-L-cysteine) is an inhibitor of New Delhi metallo-beta-lactamase-1 (NDM-1) with an IC50 of 1000 ??M.
DESCRIPTION Dacisteine (N,S-Diacetyl-L-cysteine) is an inhibitor of New Delhi metallo-beta-lactamase-1 (NDM-1) with an IC50 of 1000 μM. (TargetMol Bioactive Compound Library)
Compound Sets
5
ChEMBL Drugs
CHEMBL2106099
DrugCentral
1760
DrugCentral Approved Drugs
1760
MedChem Express Bioactive Compound Library
HY-121765
TargetMol Bioactive Compound Library
T15047
External IDs
20
Properties
(calculated by RDKit )
Molecular Weight
205.04
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
2
Rotatable Bonds
4
Ring Count
0
Aromatic Ring Count
0
cLogP
-0.14
TPSA
83.47
Fraction CSP3
0.57
Chiral centers
1.0
Largest ring
0.0
QED
0.67
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
Endogenous Metabolite
NDM-1
Pathway
Metabolic Enzyme/Protease
Source data