General
Preferred name
MUZOLIMINE
Synonyms
BAY-g 2821 ()
Edrul ()
BAY-G-2821 ()
BAY G 2821 ()
P&D ID
PD073380
CAS
37296-93-8
55294-15-0
Tags
available
drug
Drug Status
approved
withdrawn
Max Phase
Phase 4
Drug indication
Diuretic
Antihypertensive
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Muzolimine is a pyrazole and high-ceiling loop diuretic with long duration and high capacity of action. It was used for kidney failure and hypertension but was withdrawn worldwide because of severe neurological effects.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
10
BOC Sciences Bioactive Compounds
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMatrix
MedChem Express Bioactive Compound Library
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
22
Molecular Weight
271.03
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
1
Rotatable Bonds
2
Ring Count
2
Aromatic Ring Count
1
cLogP
2.56
TPSA
58.69
Fraction CSP3
0.27
Chiral centers
1.0
Largest ring
6.0
QED
0.9
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
ATC
C03CD01
Toxicity type
neurological
Solubility
Soluble in DMSO, not in water
Source data
