General
Preferred name
CHLORPROGUANIL
Synonyms
Chlorproguanil hydrochloride ()
Proguanil hydrochloride related compound f ()
Proguanil related compound f ()
Lapudrine ()
Chlorproguanil hcl ()
P&D ID
PD073325
CAS
537-21-3
15537-76-5
Tags
available
drug candidate
drug
Drug indication
Malaria
Drug Status
investigational
approved
Max Phase
Phase 3
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
1
Compound Sets
9
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
35
Properties
(calculated by RDKit )
Molecular Weight
287.07
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
5
Rotatable Bonds
2
Ring Count
1
Aromatic Ring Count
1
cLogP
2.86
TPSA
83.79
Fraction CSP3
0.27
Chiral centers
0.0
Largest ring
6.0
QED
0.43
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Indication
malaria
Target
DHFR
MOA
dihydrofolate reductase inhibitor
Source data
