General
Preferred name
ALMINOPROFEN
Synonyms
EB-382 ()
Minalfen ()
Alminoprofene ()
Alminoprofeno ()
P&D ID
PD073280
CAS
54362-71-9
74370-52-8
39718-89-3
71589-39-4
Tags
available
drug
Drug Status
approved
experimental
investigational
Max Phase
2.0
Drug indication
rheumatic disease
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Alminoprofen (EB-382) is a nonsteroidal anti-inflammatory agent (NSAID) of the phenylpropionic acid class. Alminoprofen possesses a dual anti-inflammatory action, by inhibiting both secretory phospholipase A2 (sPLA2) and COX-2[1].
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
6
ChEMBL Drugs
DrugBank
DrugCentral
DrugCentral Approved Drugs
MedChem Express Bioactive Compound Library
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
29
Molecular Weight
219.13
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
5
Ring Count
1
Aromatic Ring Count
1
cLogP
2.86
TPSA
49.33
Fraction CSP3
0.31
Chiral centers
1.0
Largest ring
6.0
QED
0.75
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
COX
Phospholipase
Pathway
Immunology/Inflammation
Metabolic Enzyme/Protease
Source data
