General
Preferred name
PIRPROFEN
Synonyms
Rangasil 400 ()
Rengasil ()
SU 21524 ()
Seflenyl ()
SU-21524 ()
Racemic pirprofen ()
P&D ID
PD073146
CAS
31793-07-4
Tags
drug
First approval
1982
1987
Drug indication
Anti-Inflammatory
Dysmenorrhea
Drug Status
experimental
approved
withdrawn
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
9
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
16
Properties
(calculated by RDKit )
Molecular Weight
251.07
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
1
Rotatable Bonds
3
Ring Count
2
Aromatic Ring Count
1
cLogP
2.9
TPSA
40.54
Fraction CSP3
0.31
Chiral centers
1.0
Largest ring
6.0
QED
0.84
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
ATC
M01AE08
Toxicity type
hepatic, gastrointestinal
Source data
