General
Preferred name
MEDROXALOL
Synonyms
RMI81968 ()
MEDROXALOL HYDROCHLORIDE ()
RMI 81,968 ()
RMI-81968 ()
RMI 81968 ()
Rmi-81,968 ()
NSC-313453 ()
RMI 81968 A ()
RMI-81968-A ()
RMI-81968 A ()
RMI-81,968-A ()
RMI 81,968 A ()
P&D ID
PD072756
CAS
56290-94-9
70161-10-3
Tags
available
drug candidate
drug
Drug Status
approved
investigational
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Medroxalol (RMI81968) is an orally active adrenergic receptor antagonist, blocks ¦Á- and ¦Â-adrenergic receptors. Medroxalol shows antihypertensive and vasodilating effects[1].
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
1
Compound Sets
6
ChEMBL Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMatrix
MedChem Express Bioactive Compound Library
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
24
Molecular Weight
372.17
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
4
Rotatable Bonds
8
Ring Count
3
Aromatic Ring Count
2
cLogP
1.86
TPSA
114.04
Fraction CSP3
0.35
Chiral centers
2.0
Largest ring
6.0
QED
0.56
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Adrenergic Receptor
Pathway
GPCR/G protein
Neuronal Signaling
Source data
