General
Preferred name
TIARAMIDE
Synonyms
FK-1160 ()
NTA-194 ()
FK 1160 ()
FK1160 ()
Tiaramide (hydrochloride) ()
RHC 2592-A ()
TIARAMIDE HYDROCHLORIDE ()
RHC 2592A ()
RHC-2592A ()
Tialamide ()
Tiaramida ()
Tiaramide HCl ()
RHC-2592 ()
NSC-289337 ()
Solantal ()
P&D ID
PD072593
CAS
35941-71-0
32527-55-2
Tags
available
drug
drug candidate
Drug Status
investigational
approved
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Tiaramide (RHC 2592-A) hydrochloride is an analgesic agent with antiallergic activity, and is also a non-steroidal, anti-inflammatory compound. Tiaramide hydrochloride inhibits histamine release[1][2].
PRICE
172
DESCRIPTION
Tiaramide hydrochloride (FK-1160) is an anti-inflammatory drug that inhibits the action of mediators released from mast cells and has direct smooth muscle relaxant properties.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
8
ChEMBL Drugs
Drug Repurposing Hub
DrugCentral
DrugCentral Approved Drugs
DrugMatrix
MedChem Express Bioactive Compound Library
ReFrame library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
36
Molecular Weight
355.08
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
1
Rotatable Bonds
4
Ring Count
3
Aromatic Ring Count
2
cLogP
0.85
TPSA
65.78
Fraction CSP3
0.47
Chiral centers
0.0
Largest ring
6.0
QED
0.88
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Indication
asthma
MOA
anti-inflammatory agent
Target
Histamine Receptor
Pathway
GPCR/G protein
Immunology/Inflammation
Neuronal Signaling
Source data
