General
Preferred name
tixocortol
Synonyms
TIXOCORTOL PIVALATE ()
Tixocortol-21-pivalate ()
Cortisol 21-thiol ()
JO-1016 ()
Tixocortol ()
Tixocortol 21-pivalate ()
P&D ID
PD072446
CAS
55560-96-8
Tags
available
drug
Drug Status
approved
investigational
Max Phase
2.0
Drug indication
Nasal congestion
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Tixocortol pivalate is a corticosteroid with some anti-inflammatory activity[1].
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
4
ChEMBL Drugs
DrugCentral
DrugCentral Approved Drugs
MedChem Express Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
21
Molecular Weight
462.24
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
2
Rotatable Bonds
3
Ring Count
4
Aromatic Ring Count
0
cLogP
4.1
TPSA
91.67
Fraction CSP3
0.81
Chiral centers
7.0
Largest ring
6.0
QED
0.66
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Endogenous Metabolite
Pathway
Metabolic Enzyme/Protease
Source data
