General
Preferred name
LEVOMENOL
Synonyms
ALPHA-BISABOLOL ()
(-)-α-Bisabolol ()
(-)-¦Á-Bisabolol ()
(-)-.alpha.-bisabolol ()
.alpha.-bisabolol, (-)- ()
Kamillosan ()
Bisabolol, (-)-.alpha. ()
.alpha.-bisabolol ()
Bisabolol, .alpha. ()
Racemic alfa-bisabolol ()
Bisabolol, alpha ()
Alpha-(-)-bisabolol ()
BISABOLOL ()
Dragosantol ()
FEMA NO. 4666 ()
Hydagen b ()
Alpha-Bisabolol ()
.alpha.-bisabolol (-)-form ()
Camilol ()
(.alpha.s,1s)-.alpha.-bisabolol ()
Bisabola-1,12-dien-8-ol ()
(–)-?-Bisabolol ()
P&D ID
PD071986
CAS
23089-26-1
Tags
available
drug
Approved by
FDA
Drug Status
investigational
approved
Max Phase
2.0
Drug indication
injury
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
INDICATION
Levomenol has been known to elicit a number of potentially beneficial pharmacological effects, including anti-irritant, anti-inflammatory, and anti-microbial actions. Bisabolol is also demonstrated to enhance the percutaneous absorption of certain molecules
DESCRIPTION
Levomenol ((-)-¦Á-Bisabolol), a monocyclic sesquiterpene alcohol, exerts antioxidant, anti-inflammatory, and anti-apoptotic activities. Levomenol also has neuroprotective effects and prevents neuronal damage and memory deficits through reduction of proinflammatory markers induced by permanent focal cerebral ischemia in mice. Levomenol attenuates nociceptive behaviour and central sensitisation in a rodent model of trigeminal neuropathic pain. Orally active[1][2].
PRICE
29
DESCRIPTION
Levomenol ((-)-??-BISABOLOL) is a sesquiterpene alcohol that has been found in the essential oils of several aromatic plants, with exerts antioxidant, anti-inflammatory, and anti-apoptotic activities.
DESCRIPTION
(-)-α-Bisabolol is isolated from essential oil of Matricaria chamomilla. It has been known to elicit a number of potentially beneficial pharmacological effects, including anti-irritant, anti-inflammatory, and anti-microbial actions. Bisabolol is also demonstrated to enhance the percutaneous absorption of certain molecules.
(Enamine Bioactive Compounds)
DESCRIPTION
Levomenol ((-)-α-BISABOLOL) is a sesquiterpene alcohol that has been found in the essential oils of several aromatic plants, with exerts antioxidant, anti-inflammatory, and anti-apoptotic activities.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
2
Organisms
0
Compound Sets
12
Cayman Chemical Bioactives
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
Enamine Bioactive Compounds
MedChem Express Bioactive Compound Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
40
Molecular Weight
222.2
Hydrogen Bond Acceptors
1
Hydrogen Bond Donors
1
Rotatable Bonds
4
Ring Count
1
Aromatic Ring Count
0
cLogP
4.23
TPSA
20.23
Fraction CSP3
0.73
Chiral centers
2.0
Largest ring
6.0
QED
0.71
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Disease Area
neurology/psychiatry, infectious disease
Indication
spasms, skin infections
Target
Apoptosis
Environmental Pollutants
Source data
