General
Preferred name
LEVMETAMFETAMINE
Synonyms
L-Desoxyephedrine ()
Levmetamfetamine cii ()
L-methamphetamine ()
Levomethamphetamine ()
(?)-Methamphetamine (hydrochloride) ()
(?)-Methamphetamine (hydrochloride) (CRM) ()
P&D ID
PD071979
CAS
33817-09-3
4846-07-5
826-10-8
Tags
natural product
drug
available
Approved by
FDA
Drug Status
approved
Drug indication
Nasal Decongestant
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
INDICATION Used over-the-counter for nasal congestion.
MOA Levomethamphetamine crosses the blood-brain-barrier and acts as a TAAR1 agonist,[3] functioning as a selective norepinephrine releasing agent in the central nervous system,
PHARMACODYNAMICS Levomethamphetamine increases norepinephrine release resulting in increased vasocontriction.
Compound Sets
6
Cayman Chemical Bioactives
13998
26616
ChEMBL Drugs
CHEMBL1927030
DrugBank
DB09571
DrugBank Approved Drugs
DB09571
DrugCentral
4641
DrugCentral Approved Drugs
4641
External IDs
34
Properties
(calculated by RDKit )
Molecular Weight
149.12
Hydrogen Bond Acceptors
1
Hydrogen Bond Donors
1
Rotatable Bonds
3
Ring Count
1
Aromatic Ring Count
1
cLogP
1.84
TPSA
12.03
Fraction CSP3
0.4
Chiral centers
1.0
Largest ring
6.0
QED
0.69
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Source data