General
Preferred name
MEBICAR
Synonyms
Tetramethylglycoluril ()
mebikar ()
Temgicoluril ()
Mebikar ()
Glycoluril, 1,3,4,6-tetramethyl- ()
Adaptol ()
P&D ID
PD071927
CAS
10095-06-4
Tags
available
drug
Drug Status
approved
Drug indication
Attention deficit hyperactivity disorder
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Temgicoluril (Tetramethylglycoluril) is an orally active antianxiety and antidepressant. Temgicoluril acts on GABA receptors to enhance GABA neurotransmission[1][2].
PRICE 29
DESCRIPTION Temgicoluril (mebikar) acts on?GABA Receptor.
DESCRIPTION Temgicoluril (mebikar) acts on GABA Receptor. (TargetMol Bioactive Compound Library)
Compound Sets
9
Cayman Chemical Bioactives
34606
ChEMBL Drugs
CHEMBL3707390
Drug Repurposing Hub
DrugCentral
4861
DrugCentral Approved Drugs
4861
MedChem Express Bioactive Compound Library
HY-139584
ReFrame library
Selleckchem Bioactive Compound Library
mebicar
TargetMol Bioactive Compound Library
T9424
External IDs
20
Properties
(calculated by RDKit )
Molecular Weight
198.11
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
0
Rotatable Bonds
0
Ring Count
2
Aromatic Ring Count
0
cLogP
-0.37
TPSA
47.1
Fraction CSP3
0.75
Chiral centers
0.0
Largest ring
5.0
QED
0.53
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
GABA Receptor
Adrenergic Receptor
Indication
anxiety
MOA
anxiolytic
Pathway
Membrane Transporter/Ion Channel
Neuroscience
Neuronal Signaling
Source data