General
Preferred name
PHENIBUT
Synonyms
3-Amino-4-phenylbutyric acid hydrochloride ()
Phenybut ()
fenigam ()
Fenibut ()
PhGABA ()
Aminophenylbutyric acid ()
β-Phenyl-γ-aminobutyric acid ()
Aminophenylbutyric acid, Fenibut, Fenigam, Phenigam, Phenybut, PhGABA, β-Phenyl-γ-aminobutyric acid ()
¦Â-phenyl-GABA ()
¦Â-Phenyl-¦Ã-aminobutyric acid ()
Aminophenylbutyric acid, Fenibut, Fenigam, Phenigam, Phenybut, PhGABA, ??Phenyl-??aminobutyric acid ()
fenigam hydrochloride ()
Aminophenylbutyric acid, Fenibut, Fenigam, Phenigam, Phenybut, PhGABA, ¦Â-Phenyl-¦Ã-aminobutyric acid, ¦Â-Phenyl-GABA ()
Phenibut (hydrochloride) ()
Phenigamma ()
4-amino-3-phenylbutyric acid ()
Phenygam ()
Dl-4-amino-3-phenylbutanoic acid ()
Phenibut (CRM) ()
P&D ID
PD071922
CAS
1078-21-3
3060-41-1
Tags
available
drug
Drug Status
approved
experimental
Drug indication
Attention deficit hyperactivity disorder
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
29
DESCRIPTION
Phenibut hydrochloride (3-Amino-4-phenylbutyric acid hydrochloride) is a GABA mimetic that acts as an agonist at GABAB receptors, blocks ??2?? subunit-containing voltage-gated calcium channels, stimulates dopamine receptors, and inhibits the actions of ??-phenethylamine
DESCRIPTION
Phenibut (Aminophenylbutyric acid) is a central depressant and derivative of the naturally occurring inhibitory neurotransmitter ??-aminobutyric acid (GABA).
DESCRIPTION
Phenibut hydrochloride (3-Amino-4-phenylbutyric acid hydrochloride) is a GABA mimetic that acts as an agonist at GABAB receptors, blocks α2δ subunit-containing voltage-gated calcium channels, stimulates dopamine receptors, and inhibits the actions of β-phenethylamine
(TargetMol Bioactive Compound Library)
DESCRIPTION
Phenibut (Aminophenylbutyric acid) is a central depressant and derivative of the naturally occurring inhibitory neurotransmitter γ-aminobutyric acid (GABA).
(TargetMol Bioactive Compound Library)
DESCRIPTION
Phenibut is an analog of GABA that acts as a GABAB receptor agonist. It is marketed as a central nervous system depressant used to treat anxiety.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
10
BOC Sciences Bioactive Compounds
ChEMBL Drugs
DrugBank
DrugCentral
DrugCentral Approved Drugs
Enamine BioReference Compounds
ReFrame library
Selleckchem Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
34
Molecular Weight
179.09
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
4
Ring Count
1
Aromatic Ring Count
1
cLogP
1.2
TPSA
63.32
Fraction CSP3
0.3
Chiral centers
1.0
Largest ring
6.0
QED
0.73
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
GABAB
GABA Receptor
GABAR
Pathway
Membrane Transporter/Ion Channel
Neuroscience
Source data
