General
Preferred name
SOMATOSTATIN
Synonyms
Somatostatin (sheep), monoacetate (salt) ()
Cyclic somatostatin Acetate(38916-34-6 free base) ()
Somatostatin-14 ()
SRIF-14 ()
monoacetate (salt) ()
Cyclic somatostatin ()
Somatostatin Acetate ()
Cyclic somatostatin Acetate ()
Somatostatina ()
Somatostatine ()
Somatostatin-14 (human, mouse, rat, porcine, bovine, ovine) (acetate) ()
P&D ID
PD071875
CAS
38916-34-6
54472-66-1
Tags
available
drug
Drug indication
Discovery agent
prostate adenocarcinoma
Drug Status
approved
investigational
Max Phase
3.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
ROE As a polypeptide chain, somatostatin is primarily eliminated via metabolism by peptidase enzymes [A20384].;
METABOLISM Somatostatin is rapidly degraded by peptidase enzymes present in cells and plasma [A20384].;
DESCRIPTION Cyclic somatostatin Acetate(38916-34-6(free base)) (Somatostatin-14) is a cyclic tetradecapeptide regulating many endocrine and nervous system functions. (TargetMol Bioactive Compound Library)
Cell lines
0
Organisms
1
Compound Sets
14
Cayman Chemical Bioactives
20809
ChEMBL Drugs
CHEMBL1823872
CZ-OPENSCREEN Bioactive Library
Drug Repurposing Hub
DrugBank
DB09099
DrugBank Approved Drugs
DB09099
DrugCentral
2997
DrugCentral Approved Drugs
2997
DrugMAP
DMIOFQE
JUMP-Target 1 Compound Set
101826531
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL1823872
MedChem Express Bioactive Compound Library
HY-P0084
ReFrame library
TargetMol Bioactive Compound Library
TP1035L
External IDs
28
Properties
(calculated by RDKit )
Molecular Weight
1636.72
Hydrogen Bond Acceptors
23
Hydrogen Bond Donors
22
Rotatable Bonds
26
Ring Count
6
Aromatic Ring Count
5
cLogP
-4.91
TPSA
613.23
Fraction CSP3
0.46
Chiral centers
15.0
Largest ring
38.0
QED
0.02
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
OPRD1, OPRM1, SSTR1, SSTR2, SSTR3, SSTR4, SSTR5
SSTR2
Endogenous Metabolite
Indication
hemorrhage
MOA
somatostatin receptor agonist
Pathway
Metabolic Enzyme/Protease
Source data