General
Preferred name
Mipomersen
Synonyms
MIPOMERSEN SODIUM ()
Mipomersen sodium salt ()
ISIS-301012 ()
Kynamro ()
ISIS 301012 ()
P&D ID
PD071759
CAS
1000120-98-8
Tags
drug
Drug indication
Familial hypercholesterolemia
Drug Status
approved
Max Phase
Phase 4
First approval
2013
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
MOE in the nucleotide image denotes nucleosides with 2'-O-(2-methoxyethyl) modification. The drug formulation contains the sodium salt, mipomersen sodium (CHEMBL2107849).
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
5
ChEMBL Approved Drugs
ChEMBL Drugs
DrugMAP
DrugMAP Approved Drugs
Guide to Pharmacology
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
14
Molecular Weight
7172.09
Hydrogen Bond Acceptors
180
Hydrogen Bond Donors
45
Rotatable Bonds
156
Ring Count
46
Aromatic Ring Count
26
cLogP
4.99
TPSA
2613.82
Fraction CSP3
0.63
Chiral centers
89.0
Largest ring
6.0
QED
0.02
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Therapeutic Class
Antisense
Source data
