General
Preferred name
FLUPHENAZINE DECANOATE
Synonyms
Fluphenazine decanoate dihydrochloride ()
Prolixin decanoate ()
SQ-10733 ()
Modecate Conc ()
Decazate ()
QD-10733 ()
Moditen depot ()
Modecate ()
Lyogen ()
NSC-169510 ()
Dapotum d ()
Fluphenazini decanoas ()
P&D ID
PD071743
CAS
5002-47-1
Tags
available
prodrug
drug
Approved by
FDA
First approval
1972
Drug indication
Antipsychotic
Schizophrenia
Drug Status
approved
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
11
Axon Medchem Screening Library
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
MedChem Express Bioactive Compound Library
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
33
Properties
(calculated by RDKit )
Molecular Weight
591.31
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
0
Rotatable Bonds
15
Ring Count
4
Aromatic Ring Count
2
cLogP
8.0
TPSA
36.02
Fraction CSP3
0.59
Chiral centers
0.0
Largest ring
6.0
QED
0.15
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Indication
schizophrenia
Target
DRD2, HTR1B, HTR4
Antipsychotic
D2/D3/5-HT2 antagonist
Dopamine Receptor
MOA
Dopamine Receptor antagonist
Therapeutic Class
Antipsychotic Agents
Pathway
GPCR/G protein
Neuronal Signaling
Source data
