General
Preferred name
PROTOKYLOL
Synonyms
Protokylol ()
PROTOKYLOL HYDROCHLORIDE ()
Caytine hydrochloride, JB-251 hydrochloride ()
Caytine ()
Asmeti ()
Palisan ()
Protoquilol ()
Ventaire ()
Protokylol HCl ()
NSC-113490 ()
P&D ID
PD071706
CAS
136-70-9
136-69-6
Tags
available
drug
biased GPCR ligand
Approved by
FDA
Drug indication
Asthma
Drug Status
vet_approved
approved
withdrawn
Max Phase
4.0
First approval
1982
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
13
BiasDB
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
ReFrame library
Selleckchem Bioactive Compound Library
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
28
Properties
(calculated by RDKit )
Molecular Weight
331.14
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
4
Rotatable Bonds
6
Ring Count
3
Aromatic Ring Count
2
cLogP
2.08
TPSA
91.18
Fraction CSP3
0.33
Chiral centers
2.0
Largest ring
6.0
QED
0.61
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
ATC
R
Target
Adrenergic Receptor
Source data
