General
Preferred name
Spinosad
Synonyms
Natroba ()
Spinosad (CRM) ()
P&D ID
PD071685
CAS
168316-95-8
Tags
available
drug
Drug Status
investigational
approved
vet_approved
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
MOA
Spinosad is a mixture of spinosyn A and spinosyn D in a 5:1 ratio. This combination causes neuronal hyperexcitation through mostly alteration of nicotinic acetylcholine receptors, which ultimately leads to lice paralysis and death.;
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
4
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
14
Molecular Weight
1476.94
Hydrogen Bond Acceptors
22
Hydrogen Bond Donors
0
Rotatable Bonds
18
Ring Count
12
Aromatic Ring Count
0
cLogP
11.36
TPSA
222.44
Fraction CSP3
0.86
Chiral centers
34.0
Largest ring
12.0
QED
0.09
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Membrane Transporter/Ion Channel
Neuronal Signaling
Target
nAChR
Source data
