General
Preferred name
GONADORELIN
Synonyms
Luteinizing Hormone Releasing Hormone (LH-RH), human ()
Luteinizing Hormone Releasing Hormone (LH-RH) ()
GONADORELIN ACETATE ()
LH-RH, human ()
GONADORELIN HYDROCHLORIDE ()
Lh Releasing Factor ()
Gonadorelin acetate mixture ()
Gonadotropin Releasing Hormone ()
Fertagyl ()
Lutrelef ()
Lutrepulse ()
Gonadorelin acetate anhydrous ()
Gonadorelin Diacetate ()
Luteinizing Hormone-Releasing Factor Diacetate Tetrahydrate ()
Luteinizing ()
Hypocrine ()
Factrel ()
GnRH ()
Cystorelin ()
Lutrepulse Kit ()
ABBOTT-41070 ()
[125I]GnRH I (human, mouse, rat) ()
Gonadotropin-releasing hormone ()
Relefact LH-RH ()
Fertiral LH-RH ()
Gonadorelin decapeptide ()
Human gonadoliberin-i ()
Luteinizing Hormone-Releasing Factor Dihydrochloride ()
AY-24,031 ()
Gonadorelin hcl ()
AY-24031 ()
Gonadorelin (acetate) ()
P&D ID
PD071679
CAS
71447-49-9
34973-08-5
9034-40-6
33515-09-2
Tags
available
drug
Approved by
FDA
First approval
1989
1982
Drug indication
Gonad-Stimulating Principle
Hypothalamic hypogonadism
Drug Status
approved
vet_approved
Max Phase
Phase 4
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Compound Sets
13
AdooQ Bioactive Compound Library
Cayman Chemical Bioactives
Drug Repurposing Hub
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
Guide to Pharmacology
LSP-MoA library (Laboratory of Systems Pharmacology)
ReFrame library
TargetMol Bioactive Compound Library
External IDs
58
Properties
(calculated by RDKit )
Molecular Weight
1181.57
Hydrogen Bond Acceptors
15
Hydrogen Bond Donors
17
Rotatable Bonds
31
Ring Count
6
Aromatic Ring Count
4
cLogP
-4.18
TPSA
472.13
Fraction CSP3
0.47
Chiral centers
8.0
Largest ring
6.0
QED
0.01
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Pathway
Endocrinology/Hormones
Target
5-alpha Reductase
5-?? reductase
5-¦Á reductase
GNRHR
MOA
Reductase
gonadotropin releasing factor hormone receptor agonist
Indication
cystic ovaries, reproductive synchrony
Therapeutic Class
Fertility Agents
Source data