General
Preferred name
GONADORELIN
Synonyms
GnRH-I acetate(33515-09-2 free base) ()
LH-RH, human ()
GnRH-I acetate ()
GONADORELIN ACETATE ()
GONADORELIN HYDROCHLORIDE ()
Gonadorelin (acetate) ()
Lutrepulse Kit ()
GnRH ()
Gonadorelin acetate mixture ()
Lutrelef ()
Luteinizing Hormone-Releasing Factor Diacetate Tetrahydrate ()
Gonadorelin acetate anhydrous ()
Fertagyl ()
Luteinizing ()
Gonadotropin Releasing Hormone ()
Hypocrine ()
Gonadorelin Diacetate ()
ABBOTT-41070 ()
Lh Releasing Factor ()
[125I]GnRH I (human, mouse, rat) ()
Fertiral LH-RH ()
Gonadoreline ()
Gonadorelina ()
Gonadotropin-releasing hormone ()
Gonadorelin decapeptide ()
Relefact LH-RH ()
AY-24,031 ()
AY-24031 ()
Gonadorelin hcl ()
Factrel ()
Luteinizing Hormone-Releasing Factor Dihydrochloride ()
P&D ID
PD071679
CAS
71447-49-9
34973-08-5
9034-40-6
33515-09-2
Tags
available
drug
Approved by
FDA
First approval
1982
1989
Drug indication
Hypothalamic hypogonadism
Infertility
cocaine dependence
Drug Status
vet_approved
approved
Max Phase
4.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
GnRH-I acetate in release of biologically active Follicle-Stimulating Hormone (FSH) and Luteinizing Hormone (LH) in the blood.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
13
AdooQ Bioactive Compound Library
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
Guide to Pharmacology
LSP-MoA library (Laboratory of Systems Pharmacology)
ReFrame library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
63
Molecular Weight
1181.57
Hydrogen Bond Acceptors
15
Hydrogen Bond Donors
17
Rotatable Bonds
31
Ring Count
6
Aromatic Ring Count
4
cLogP
-4.18
TPSA
472.13
Fraction CSP3
0.47
Chiral centers
8.0
Largest ring
6.0
QED
0.01
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Gnrhr - gonadotropin releasing hormone receptor (Norway rat)
5-alpha Reductase
5-¦Á reductase
GNRHR
MOA
Reductase
gonadotropin releasing factor hormone receptor agonist
Indication
cystic ovaries, reproductive synchrony
Therapeutic Class
Fertility Agents
Source data
