General
Preferred name
BETAMETHASONE ACETATE
Synonyms
Betamethasone acetate component of celestone soluspan ()
Betamethasone 21-acetate ()
NSC-759196 ()
Betamethasone acetate component of osurnia ()
P&D ID
PD071667
CAS
987-24-6
Tags
available
prodrug
drug
Approved by
FDA
First approval
1965
Drug Status
vet_approved
approved
Max Phase
4.0
Drug indication
Tendinopathy
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Betamethasone acetate is a glucocorticoid corticosteroid. Betamethasone acetate induces fetal lung maturation in preterm sheep[1].
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
5
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugCentral
DrugCentral Approved Drugs
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
25
Molecular Weight
434.21
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
2
Rotatable Bonds
3
Ring Count
4
Aromatic Ring Count
0
cLogP
2.47
TPSA
100.9
Fraction CSP3
0.71
Chiral centers
8.0
Largest ring
6.0
QED
0.66
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Indication
corticosteroid-responsive dermatoses
Target
NR3C1
Aquaporin
Glucocorticoid Receptor
MOA
Glucocorticoid Receptor agonist
Pathway
Immunology/Inflammation
Membrane Transporter/Ion Channel
Vitamin D Related/Nuclear Receptor
Source data
