General
Preferred name
PYRITHIONE
Synonyms
PYRITHIONE ZINC ()
zinc pyrithione ()
2-Mercaptopyridine N-oxide (sodium) ()
PYRITHIONE SODIUM ()
Zinc pyrithone ()
Pyrithione zincique ()
Piritiona cincica ()
Revlon Zp11 ()
Sebulon shampoo ()
Head & Shoulders Conditioner ()
NSC-290409 ()
Pyrithione zinc derivative ()
Zinc pyridinethione ()
Zincpolyanemine ()
Sodium omadine ()
Tomicide s ()
Sodium pyrithione ()
AL-02725 ()
AL02725 ()
Omadine sodium ()
NSC-4483 ()
Omacide 24 ()
Topcide 280 ()
Pyrithione sodium salt ()
P&D ID
PD071658
CAS
13463-41-7
1121-31-9
109702-19-4
3811-73-2
15922-78-8
Tags
available
drug
drug candidate
Drug indication
Discovery agent
Drug Status
approved
Max Phase
4.0
First approval
1986
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Pyrithione is an antimicrobial agent used for the treatment of dandruff and seborrheic dermatitis. It has a broad antimicrobial spectrum of activity, including fungi, gram-positive and gram-negative bacteria
(Enamine Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
2
Organisms
1
Compound Sets
17
ChEMBL Approved Drugs
ChEMBL Drugs
CZ-OPENSCREEN Bioactive Library
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMatrix
Enamine Bioactive Compounds
EU-OPENSCREEN Bioactive Compound Library
Guide to Pharmacology
LSP-MoA library (Laboratory of Systems Pharmacology)
MedChem Express Bioactive Compound Library
NCATS Inxight Approved Drugs
ReFrame library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
71
Molecular Weight
127.01
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
1
Rotatable Bonds
0
Ring Count
1
Aromatic Ring Count
1
cLogP
0.61
TPSA
26.94
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.31
Structural alerts
1
aggregator (Aggregator Advisor)
Aggregators
Related compounds
Custom attributes
(extracted from source data)
Target
Bacterial
Pathway
Anti-infection
Source data
