General
Preferred name
LITHIUM CITRATE
Synonyms
LITHIUM CITRATE HYDRATE ()
Lithium citrate tribasic tetrahydrate ()
Trilithium citrate tetrahydrate ()
Lithium citrate (tetrahydrate) ()
Litarex (tetrahydrate) ()
Trilithium citrate tetrahydrate, Lithium citrate tribasic tetrahydrate ()
Citric acid trilithium salt tetrahydrate ()
LITHIUM CITRATE ANHYDROUS ()
Lithium citrate tetrahydrate ()
Li-Liquid ()
Litarex ()
NSC-758700 ()
Lithium (as citrate) ()
Lithonate s ()
Lithium Citrate ()
Citric acid trilithium salt ()
P&D ID
PD071653
CAS
6080-58-6
919-16-4
6680-58-6
879647-30-0
10377-38-5
1313437-84-1
Tags
available
drug
Drug Status
approved
Max Phase
4.0
Drug indication
bipolar I disorder
First approval
1980
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
29
DESCRIPTION
Citric acid trilithium salt tetrahydrate (Lithium citrate tribasic tetrahydrate) , the active component of Lithium, is a medicine used in the therapy of psychiatric disease. It has shown the effects of signaling pathways and metabolic in the brain based on the particular disease and clinical condition model. According to the reports, Citric acid trilithium salt tetrahydrate was used as a mood stabilizer when treating bipolar mood disorders (BD) and lower the risk of self-harm in BD patient. In addition,Citric acid trilithium salt tetrahydrate has been the choice drug in the therapy of acute manic episodes.Citric acid trilithium salt tetrahydrate also could dissolve uric acid crystals in urine achieved from patients with gout. Besides,Citric acid trilithium salt tetrahydrate have some dose-dependent side-effects. The the main side-effects of Lithium Citrate is the tendency to inhibit the prostatic acid phosphatase enzyme (PAP), which result in the accumulation of PAP.
(TargetMol Bioactive Compound Library)
DESCRIPTION
Lithium citrate is used as a mood stabilizer, and is used for treatment of depression and mania. It is often used in bipolar disorder treatment.
(Enamine Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
11
CeMM library of unique drugs (CLOUD)
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
Enamine Bioactive Compounds
Enamine BioReference Compounds
MedChem Express Bioactive Compound Library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
46
Molecular Weight
210.05
Hydrogen Bond Acceptors
7
Hydrogen Bond Donors
1
Rotatable Bonds
5
Ring Count
0
Aromatic Ring Count
0
cLogP
-14.24
TPSA
140.62
Fraction CSP3
0.5
Chiral centers
0.0
Largest ring
0.0
QED
0.44
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
MOA
Unknown molecular target
Dehydrogenase inhibitor
GluR potentiator
GSK-3 inhibitor
Target
Inositol-1(or 4)-monophosphatase 1
Glycogen synthase kinase-3
Bacterial
GSK-3β
IMPDH
mGluR3
GSK-3¦Â
Apoptosis
Endogenous Metabolite
Pathway
Chromatin/Epigenetic
Metabolism
Microbiology/virology
Neuroscience
PI3K/Akt/mTOR signaling
Stem Cells
Anti-infection
Metabolic Enzyme/Protease
Source data
